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Article

The regulation of TACE catalytic function by its prodomain.

Molecular biology reports - 1 Apr 2009

Li Xiaoou, Yan Yuan, Huang Wei, Yang Yuzhen, Wang Hongwei, Chang Liwen

Abstract excerpt

AIM: To study the function of the prodomain of ADAM17 (TACE) and to develop an approach for interfering with inflammation processes. METHOD: The expression plasmids of the TACE ectodomain (T1300), prodomain (T591), signal peptide and prodomain (T648), full length (T2472), and the turncated TACE without prodomain (T57-T1824) were constructed and designated as pET-28a-T300, pET-28a-T591, pIRES2-EGFP-648,...

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Source

Identifiers

PMID: 18386160
DOI: 10.1007/s11033-008-9224-5

Genes

TNF
ADAM17

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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