Article
Merlin--rapid analysis of dense genetic maps using sparse gene flow trees.
Nature genetics - 1 Jan 2002
Abecasis Gonçalo R, Cherny Stacey S, Cookson William O, Cardon Lon R
Abstract excerpt
Efforts to find disease genes using high-density single-nucleotide polymorphism (SNP) maps will produce data sets that exceed the limitations of current computational tools. Here we describe a new, efficient method for the analysis of dense genetic maps in pedigree data that provides extremely fast solutions to common problems such as allele-sharing analyses and haplotyping. We show that sparse binary trees...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.