Sibship reconstruction from genetic data with typing errors.

Abstract excerpt

Likelihood methods have been developed to partition individuals in a sample into full-sib and half-sib families using genetic marker data without parental information. They invariably make the critical assumption that marker data are free of genotyping errors and mutations and are thus completely reliable in inferring sibships. Unfortunately, however, this assumption is rarely tenable for virtually all kinds of...

Topics

• Algorithms
• Computer Simulation
• Gene Frequency
• Genetic Markers
• Genetics, Population
• Genotype
• Likelihood Functions
• Models, Genetic
• Research Design
• Sibling Relations