Article
Detecting pedigree relationship errors.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012
Sun Lei
Abstract excerpt
Pedigree relationship errors often occur in family data collected for genetic studies, and unidentified errors can lead to either increased false positives or decreased power in both linkage and association analyses. Here we review several allele sharing, as well as likelihood-based statistics, that were proposed to efficiently extract genealogical information from available genome-wide marker data, and the...
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