Article
ACE gene polymorphism as a prognostic indicator in patients with type 2 diabetes and established renal disease.
Diabetes care - 1 Dec 2001
Fava S, Azzopardi J, Ellard S, Hattersley A T
Abstract excerpt
OBJECTIVE: To investigate whether the DD genotype is a predictor of mortality and of the decline in renal function in patients with type 2 diabetes and established nephropathy. RESEARCH DESIGN AND METHODS: A total of 56 such patients of Maltese Caucasian descent were recruited, and their ACE genotype was determined. Serum creatinine was estimated approximately every 4 months. The glomerular filtration rate (GFR)...
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