Article
Angiotensin-converting enzyme insertion/deletion polymorphism and prognosis of IgA nephropathy.
Nephron - 1 Oct 2000
Syrjänen J, Huang X H, Mustonen J, Koivula T, Lehtimäki T, Pasternack A
Abstract excerpt
BACKGROUND/AIM: Well-known factors for a poor prognosis in IgA nephropathy (IgAN) are hypertension, proteinuria, and renal insufficiency at the time of diagnosis. Also hypertriglyceridemia and hyperuricemia seem to play a role in the progression of IgAN. Angiotensin-converting enzyme (ACE) gene I/D polymorphism has been associated with cardiovascular diseases and with progression of IgAN. We, therefore,...
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