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Article

ADAMTS13 predicts renal and cardiovascular events in type 2 diabetic patients and response to therapy.

Diabetes - 1 Oct 2013

Rurali Erica, Noris Marina, Chianca Antonietta, Donadelli Roberta, Banterla Federica, Galbusera Miriam, Gherardi Giulia, Gastoldi Sara, Parvanova Aneliya, Iliev Ilian, Bossi Antonio, Haefliger Carolina, Trevisan Roberto, Remuzzi Giuseppe, Ruggenenti Piero

Abstract excerpt

In patients with diabetes, impaired ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeats, member 13) proteolysis of highly thrombogenic von Willebrand factor (VWF) multimers may accelerate renal and cardiovascular complications. Restoring physiological VWF handling might contribute to ACE inhibitors' (ACEi) reno- and cardioprotective effects. To assess how Pro618Ala ADAMTS13 variants and...

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Share to Diabetic Angiopathies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Angiotensin-Converting Enzyme Inhibitors

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Source

Open in PubMed Open full text

Identifiers

PMID: 23733198
DOI: 10.2337/db13-0530
PMCID: PMC3781447

Genes

ADAMTS13
VWF
ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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