Article
ACE genotype, phenotype and all-cause mortality in different cohorts of patients with type 1 diabetes.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Jun 2015
Færch Louise H, Sejling Anne-Sophie, Lajer Maria, Tarnow Lise, Thorsteinsson Birger, Pedersen-Bjergaard Ulrik
Abstract excerpt
AIMS: Carrying the D-allele of the angiotensin-converting enzyme (ACE) I/D polymorphism and high ACE activity are prognostic factors in diabetic nephropathy, which predicts mortality in type 1 diabetes. We studied the association between the ACE D-allele and ACE phenotype and long-term all-cause mortality in three single-institution outpatient cohorts. METHODS: Genotype-based analyses were performed in 269...
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