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Article

Prognostic value of angiotensin-I converting enzyme I/D polymorphism for nephropathy in type 1 diabetes mellitus: a prospective study.

Journal of the American Society of Nephrology : JASN - 1 Mar 2001

Hadjadj Samy, Belloum Riadh, Bouhanick Béatrice, Gallois Yves, Guilloteau Gérard, Chatellier Gilles, Alhenc-Gelas François, Marre Michel

Abstract excerpt

Angiotensin-I converting enzyme (ACE) regulates renal hemodynamics. Its insertion/deletion (I/D) polymorphism, which determines most of ACE interindividual variance, was proposed as a genetic marker for diabetic nephropathy. A substitution (M235T) polymorphism in angiotensinogen (AGT) may interact with ACE I/D polymorphism for the risk of diabetic nephropathy, but their prognostic values have to be established by...

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Identifiers

PMID: 11181802
DOI: 10.1681/ASN.V123541

Genes

ACE
AGT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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