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Article

Structural implications of a Val-->Glu mutation in transmembrane peptides from the EGF receptor.

Biophysical journal - 1 Dec 2001

Sharpe S, Grant C W, Barber K R, Giusti J, Morrow M R

Abstract excerpt

Certain specific point mutations within the transmembrane domains of class I receptor tyrosine kinases are known to induce altered behavior in the host cell. An internally controlled pair of peptides containing the transmembrane portion of the human epidermal growth factor (EGF) receptor (ErbB-1) was examined in fluid, fully hydrated lipid bilayers by wide-line 2H-NMR for insight into the physical basis of this...

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Source

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Identifiers

PMID: 11720988
DOI: 10.1016/S0006-3495(01)75958-9
PMCID: PMC1301782

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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