Article
A single-residue deletion alters the lipid selectivity of a K+ channel-associated peptide in the beta-conformation: spin label electron spin resonance studies.
Biophysical journal - 1 Nov 1997
Horváth L I, Knowles P F, Kovachev P, Findlay J B, Marsh D
Abstract excerpt
Lipid-peptide interactions with the 27-residue peptide of sequence KLEALYILMVLGFFGFFTLGIMLSYIR reconstituted as beta-sheet assemblies in dimyristoylphosphatidylcholine bilayers have been studied by electron spin resonance (ESR) spectroscopy with spin-labeled lipids. The peptide corresponds to residues 42-68 of the IsK voltage-gated K+ channel protein and contains the single putative transmembrane span of this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
