Article
A single-residue deletion alters the lipid selectivity of a K+ channel-associated peptide in the beta-conformation: spin label electron spin resonance studies.
Biophysical journal - 1 Nov 1997
Horváth L I, Knowles P F, Kovachev P, Findlay J B, Marsh D
Abstract excerpt
Lipid-peptide interactions with the 27-residue peptide of sequence KLEALYILMVLGFFGFFTLGIMLSYIR reconstituted as beta-sheet assemblies in dimyristoylphosphatidylcholine bilayers have been studied by electron spin resonance (ESR) spectroscopy with spin-labeled lipids. The peptide corresponds to res...
Topics
- Amino Acid Sequence
- Dimyristoylphosphatidylcholine
- Electron Spin Resonance Spectroscopy
- Lipid Metabolism
- Membrane Proteins
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Peptides
- Phospholipids
- Potassium Channels
- Protein Conformation
- Protein Structure, Secondary
- Spectroscopy, Fourier Transform Infrared