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A Genetically Engineered Reporter System Designed for 2H-MRI Allows Quantitative In Vivo Mapping of Transgene Expression

11 Nov 2024

Abstract excerpt

High Resolution Image Download MS PowerPoint Slide The ability to obtain quantitative spatial information on subcellular processes of deep tissues in vivo has been a long-standing challenge for molecular magnetic resonance imaging (MRI) approaches. This challenge remains even more so for quantifying readouts of genetically engineered MRI reporters. Here, we set to overcome this challenge with a molecular system...

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PMID: 39527270
DOI: 10.1021/jacs.4c09572

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