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Article

Characterization of the proto-oncogenic and mutant forms of the transmembrane region of Neu in micelles.

The Journal of biological chemistry - 4 Jun 2004

Houliston R Scott, Hodges Robert S, Sharom Frances J, Davis James H

Abstract excerpt

We have investigated peptides corresponding to the complete transmembrane region of both proto-oncogenic (Val(664)) and mutant (Glu(664)) forms of the receptor Neu in detergent micelles by NMR and CD spectroscopy. Both forms of the peptide appear to adopt similar levels of helicity and dimeric interactions based on the analysis of CD spectra and nuclear Overhauser effect connectivity profiles. There are...

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PMID: 15051716
DOI: 10.1074/jbc.M401919200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization of the proto-oncogenic and mutant forms of the transmembrane region of Neu in micelles.PMID 15051716Read ↗

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