Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of RKIP expression during the carcinogenic evolution of endometrial cancer.

Journal of clinical pathology - 1 Feb 2012

Martinho Olga, Faloppa Carlos Chaves, Neto Cristovam Scapulatempo, Longatto-Filho Adhemar, Baiocchi Glauco, da Cunha Isabela Werneck, Soares Fernando Augusto, Fregnani José Humberto Tavares Guerreiro, Reis Rui Manuel

Abstract excerpt

AIMS: Endometrial cancer is one of the most common cancers in women worldwide, but there is a lack of diagnostic markers for early detection of these tumours. The raf kinase inhibitory protein (RKIP) negatively regulates the Raf/MEK/ERK pathway, and the downregulation of RKIP is associated with tumour progression and metastasis in several human neoplasms. The aim of this study was to assess the expression levels...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endometrial Hyperplasia

Share to Endometrial Neoplasms

Share to Polyps

Share to Prognosis

Share to Survival Analysis

Share to Tissue Array Analysis

Source

Identifiers

PMID: 22031589
DOI: 10.1136/jclinpath-2011-200358

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of RKIP expression during the carcinogenic evolution of endometrial cancer.PMID 22031589Read ↗

Survey of Raf Kinase Inhibitor Protein (RKIP) in Multiple Cancer TypesSemantic proximity Read ↗

Biological and therapeutic implications of RKIP in Gastrointestinal Stromal Tumor (GIST): an integrated transcriptomic and proteomic analysisSemantic proximity Read ↗

RKIP inhibits the malignant phenotypes of gastric cancer cells.Semantic proximity Read ↗

Raf Kinase Inhibitor Protein Expression in a Survival Analysis of Colorectal Cancer PatientsSemantic proximity Read ↗

Correlation among RKIP expression, NF-κB p65 levels, and T-lymphocyte subsets in gastric cardia adenocarcinoma.Semantic proximity Read ↗

Raf kinase inhibitory protein (RKIP): A physiological regulator and future therapeutic targetSemantic proximity Read ↗

Raf kinase inhibitor protein: mechanism of loss of expression and association with genomic instabilitySemantic proximity Read ↗

The Role of RKIP in the Regulation of EMT in the Tumor MicroenvironmentSemantic proximity Read ↗

A dualistic model for endometrial carcinogenesis based on immunohistochemical and molecular genetic analyses.Semantic proximity Read ↗

Relationship of Signaling Pathways between RKIP Expression and the Inhibition of EMT-Inducing Transcription Factors SNAIL1/2, TWIST1/2 and ZEB1/2Semantic proximity Read ↗

Raf kinase inhibitory protein regulates Raf-1 but not B-Raf kinase activation.Semantic proximity Read ↗

Expression of phosphorylated raf kinase inhibitor protein (pRKIP) is a predictor of lung cancer survivalSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.