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Article

Searching for genetic determinants of human aging and longevity: opportunities and challenges.

Mechanisms of ageing and development - 1 Jan 2002

Vijg Jan, van Orsouw Nathalie

Abstract excerpt

One way of testing possible causal relationships between various functional pathways and aging and longevity processes is to comparatively analyze groups of elderly individuals with select phenotypes for sequence variation in all genes participating in these pathways. Such direct association analysis to identify 'candidate pathways' in aging and longevity is theoretically feasible, with the complete sequence of...

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PMID: 11718812
DOI: 10.1016/s0047-6374(01)00346-3

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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