Article
Genome-wide association studies in aging-related processes such as diabetes mellitus, atherosclerosis and cancer.
Experimental gerontology - 1 Jan 2008
Kronenberg Florian
Abstract excerpt
Recent technological developments allow to genotype several hundreds of thousands of genetic variants in a single person in one step. This enables genome-wide association studies (GWAS) by genotyping a large number of patients with diseases of interest and controls at reasonable costs. Compared to a hypothesis-driven candidate gene approach the hypothesis-free GWAS can identify new susceptibility genes without...
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