Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Requirement for yeast RAD26, a homolog of the human CSB gene, in elongation by RNA polymerase II.

Molecular and cellular biology - 1 Dec 2001

Lee S K, Yu S L, Prakash L, Prakash S

Abstract excerpt

Mutations in the human CSB gene cause Cockayne syndrome (CS). In addition to increased photosensitivity, CS patients suffer from severe developmental abnormalities, including growth retardation and mental retardation. Whereas a deficiency in the preferential repair of UV lesions from the transcribed strand accounts for the increased photosensitivity of CS patients, the reason for developmental defects in these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cockayne Syndrome
Share to DNA Helicases
Share to DNA Repair Enzymes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Poly-ADP-Ribose Binding Proteins

Share to RNA Polymerase II

Share to Schizosaccharomyces pombe Proteins

Share to Ultraviolet Rays

Source

Open in PubMed Open full text

Identifiers

PMID: 11713297
DOI: 10.1128/MCB.21.24.8651-8656.2001
PMCID: PMC100025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Requirement for yeast RAD26, a homolog of the human CSB gene, in elongation by RNA polymerase II.PMID 11713297Read ↗

Requirement of yeast RAD2, a homolog of human XPG gene, for efficient RNA polymerase II transcription. implications for Cockayne syndrome.Semantic proximity Read ↗

Regulation of active genome integrity and expression by Rad26p.Semantic proximity Read ↗

Alterations in the CSB gene in three Italian patients with the severe form of Cockayne syndrome (CS) but without clinical photosensitivity.Semantic proximity Read ↗

Deletion of the CSB homolog, RAD26, yields Spt(-) strains with proficient transcription-coupled repair.Semantic proximity Read ↗

Cockayne syndrome B protein acts as an ATP-dependent processivity factor that helps RNA polymerase II overcome nucleosome barriers.Semantic proximity Read ↗

Defective transcription-coupled repair in Cockayne syndrome B mice is associated with skin cancer predisposition.Semantic proximity Read ↗

Prolonged stalling of RNA Polymerase II at DNA damage explains phenotypical differences between Cockayne and UV-sensitive syndromesSemantic proximity Read ↗

Mechanistic insights into the regulation of transcription and transcription-coupled DNA repair by Cockayne syndrome protein B.Semantic proximity Read ↗

A ubiquitin-binding domain in Cockayne syndrome B required for transcription-coupled nucleotide excision repair.Semantic proximity Read ↗

Recruitment of the putative transcription-repair coupling factor CSB/ERCC6 to RNA polymerase II elongation complexes.Semantic proximity Read ↗

UVB radiation-induced cancer predisposition in Cockayne syndrome group A (Csa) mutant mice.Semantic proximity Read ↗

Mechanism of Rad26-assisted rescue of stalled RNA polymerase II in transcription-coupled repair.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.