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Article

Role of porins for uptake of antibiotics by Mycobacterium smegmatis.

Antimicrobial agents and chemotherapy - 1 Sept 2008

Danilchanka Olga, Pavlenok Mikhail, Niederweis Michael

Abstract excerpt

The outer membrane of mycobacteria presents an effective permeability barrier for many antibiotics. Transport pathways across this membrane are unknown for most drugs. Here, we examined which antibiotics utilize the porin pathway across the outer membrane of the model organism Mycobacterium smegmatis. Deletion of the porins MspA and MspC drastically increased the resistance of M. smegmatis ML10 to beta-lactam...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18559650
DOI: 10.1128/AAC.00239-08
PMCID: PMC2533485

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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