Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overexpression of mutated IkappaBalpha inhibits vascular smooth muscle cell proliferation and intimal hyperplasia formation.

Journal of vascular surgery - 1 Oct 2003

Zuckerbraun Brian S, McCloskey Carol A, Mahidhara Raja S, Kim Peter K M, Taylor Bradley S, Tzeng Edith

Abstract excerpt

PURPOSE: Vascular injury and inflammation are associated with elaboration of a number of cytokines that signal through multiple pathways to act as smooth muscle cell (SMC) mitogens. Activation of the nuclear factor-kappa B (NF-kappaB) transcription factor is essential for SMC proliferation in vit...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carotid Arteries
Share to Cyclin-Dependent Kinase Inhibitor p21
Share to Fetal Blood

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyperplasia

Share to I-kappa B Proteins

Share to NF-KappaB Inhibitor alpha

Share to Proliferating Cell Nuclear Antigen

Share to Tunica Intima

Source

Identifiers

PMID: 14560235
DOI: 10.1016/s0741-5214(03)00427-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14560235-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overexpression of mutated IkappaBalpha inhibits vascular smooth muscle cell proliferation and intimal hyperplasia formation.PMID 14560235Read ↗

Smooth muscle-selective inhibition of nuclear factor-κB attenuates smooth muscle phenotypic switching and neointima formation following vascular injury.Semantic proximity Read ↗

Regulation of vascular smooth muscle cell proliferation: role of NF-kappaB revisited.Semantic proximity Read ↗

Modulating vascular intimal hyperplasia using HSV-1 mutant requires activated MEK.Semantic proximity Read ↗

Effect of Activated Protein Kinase C Beta Type Mediated Phosphorylation of Signal Transducer and Activator of Transcription 4 on Proliferation and Phenotypic Transformation of Vascular Smooth Muscle Cells After Vascular Injury Induced by Nano-SiO₂.Semantic proximity Read ↗

Stress and vascular responses: mitogen-activated protein kinases and activator protein-1 as promising therapeutic targets of vascular remodeling.Semantic proximity Read ↗

Adenoviral constructs encoding phosphorylation-competent full-length and truncated forms of the human retinoblastoma protein inhibit myocyte proliferation and neointima formation.Semantic proximity Read ↗

Rho GTPase, Rac1, regulates Skp2 levels, vascular smooth muscle cell proliferation, and intima formation in vitro and in vivo.Semantic proximity Read ↗

Receptor interacting protein 3 suppresses vascular smooth muscle cell growth by inhibition of the phosphoinositide 3-kinase-Akt axis.Semantic proximity Read ↗

Effects of dominant-negative c-Jun on platelet-derived growth factor-induced vascular smooth muscle cell proliferation.Semantic proximity Read ↗

Deletion of Krüppel-like factor 4 in endothelial and hematopoietic cells enhances neointimal formation following vascular injury.Semantic proximity Read ↗

Intermedin reduces neointima formation by regulating vascular smooth muscle cell phenotype via cAMP/PKA pathway.Semantic proximity Read ↗

Adenoviral delivery of a constitutively active retinoblastoma mutant inhibits neointima formation in a human explant model for vein graft disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.