Article
Cholecystokinin2 receptor-deficient mice display altered function of brain dopaminergic system.
Psychopharmacology - 1 Nov 2001
Kõks S, Volke V, Veraksits A, Rünkorg K, Sillat T, Abramov U, Bourin M, Huotari M, Männistö P T, Matsui T, Vasar E
Abstract excerpt
RATIONALE: Cholecystokinin (CCK) has been shown to coexist and interact with dopamine in the regulation of behaviour. Two different CCK receptors (CCK1 and CCK2) have an opposite influence on the activity of dopamine neurons. Stimulation of CCK2 receptors decreases the release of dopamine and that receptor could mediate the neuroleptic-like effect of CCK. OBJECTIVE: To investigate the activity of the dopaminergic...
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