Article
Specificity of behavioral and neurochemical dysfunction in the chakragati mouse: a novel genetic model of a movement disorder.
Brain research - 16 Apr 1993
Fitzgerald L W, Ratty A K, Teitler M, Gross K W, Glick S D
Abstract excerpt
The chakragati (ckr) mouse is a transgenic insertional mutant that displays lateralized circling behavior, locomotor hyperactivity, hyperexcitability as well as body weight deficits. The mutation is autosomal and recessive. We have previously found that ckr mice have bilateral asymmetric elevatio...
Topics
- Animals
- Autoradiography
- Behavior, Animal
- Brain Chemistry
- Corpus Striatum
- Disease Models, Animal
- Functional Laterality
- Limbic System
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Mice, Transgenic
- Motor Activity
- Movement Disorders
- Neural Pathways
- Phenotype
- Receptors, Dopamine
- Stereotyped Behavior