Article
Dopaminergic brain system in the quaking mutant mouse.
Pharmacology, biochemistry, and behavior - 1 Mar 1995
Nikulina E M, Skrinskaya J A, Avgustinovich D F, Popova N K
Abstract excerpt
Quaking mice (qk/qk), autosomal recessive mutants with central nervous system dysmyelinization, characterized behaviorally by abnormal locomotion and tremor, are found to have altered brain dopaminergic system parameters, in comparison with phenotypically normal heterozygous littermates. Dopamine metabolism is enhanced in structures of both nigrostriatal and mesolimbic systems, as revealed by increased...
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