Article
Hepatitis B virus X protein induced expression of the Nur77 gene.
Biochemical and biophysical research communications - 16 Nov 2001
Lee M O, Kang H J, Cho H, Shin E C, Park J H, Kim S J
Abstract excerpt
Hepatitis B virus (HBV) X protein (HBx) plays an essential role in development of HBV-associated hepatocellular carcinoma (HCC). Recently, we reported that HBx induces Fas Ligand (FasL) expression, which may help HCC cells to evade host-immune surveillance. The aim of this study was to investigat...
Topics
- Carcinoma, Hepatocellular
- DNA-Binding Proteins
- Fas Ligand Protein
- Hepatitis B
- Hepatitis B virus
- Humans
- Liver Neoplasms
- Membrane Glycoproteins
- Mutation
- Nuclear Receptor Subfamily 4, Group A, Member 1
- Oligonucleotides, Antisense
- Promoter Regions, Genetic
- RNA, Messenger
- Receptors, Cytoplasmic and Nuclear
- Receptors, Steroid
- Trans-Activators
- Transcription Factors
- Transcriptional Activation