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Article

Nur77: a potential therapeutic target in cancer

26 Apr 2012

Abstract excerpt

INTRODUCTION: The orphan nuclear receptor Nur77 (also known as NR4A1, NGFIB, TR3, TIS1, NAK-1, or N10) is a unique transcription factor encoded by an immediate early gene. Nur77 signaling is deregulated in many cancers and constitutes an important molecule for drug targeting. AREAS COVERED: Nur77 as a versatile transcription factor that displays distinct dual roles in cell proliferation and apoptosis. In...

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Identifiers

PMID: 22537097
DOI: 10.1517/14728222.2012.680958

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