Article

Nur77 Inhibit β-catenin Expression to Mediate Hepatoblastoma Progression and Therapeutic Effect of Cisplatin

2023-09-25

Abstract excerpt

Hepatoblastoma (HB) is the most common malignant tumor in children under 5 years old, but its pathogenesis remains unclear. Nur77 has been reported to be an important regulator for cancer progression in various cancer types. This study found that Nur77 was downregulated in HB tumors, compared with paracancer tissue. Knockout or overexpression of Nur77 in HB tumor cell line HepG2 and HuH6 could significantly enhanc...

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Literature Corpus work: 00a5f493-a787-5b27-8e74-c3d32901cc60
DOI: 10.21203/rs.3.rs-3350840/v1

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