Article
CCR5Delta32 and promoter polymorphisms are not correlated with initial virological or immunological treatment response.
AIDS (London, England) - 23 Nov 2001
Brumme Z L, Chan K J, Dong W, Hogg R, O'Shaughnessy M V, Montaner J S, Harrigan P R
Abstract excerpt
OBJECTIVE: Natural genetic polymorphisms within the CCR5 gene and promoter have been linked to patterns of HIV-1 clinical disease progression in untreated individuals. The objective of this retrospective study was to assess the influence of the CCR5Delta32 mutation and promoter polymorphisms on virological and immunological treatment outcome in 436 antiretroviral-naive individuals initiating their first therapy,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
