Article
Structure and polymorphisms of human aryl hydrocarbon receptor repressor (AhRR) gene in a French population: relationship with CYP1A1 inducibility and lung cancer.
Pharmacogenetics - 1 Jun 2003
Cauchi Stéphane, Stücker Isabelle, Cénée Sylvie, Kremers Pierre, Beaune Philippe, Massaad-Massade Liliane
Abstract excerpt
OBJECTIVE: The aryl hydrocarbon receptor repressor (AhRR) protein may dimerize with the AhR nuclear translocator (ARNT) and may compete with the aryl hydrocarbon receptor (AhR) to bind the xenobiotic responsive elements. The result is a negative feedback mechanism that involves a down regulation...
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