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Article

Focal adhesion kinase and Src mediate integrin regulation of insulin receptor phosphorylation.

FEBS letters - 2 Nov 2001

El Annabi S, Gautier N, Baron V

Abstract excerpt

We show here that phosphorylation of the insulin receptor and insulin receptor substrate-1 is increased when suspended cells are replated on fibronectin. This is not due to decreased numbers of cell surface receptors, alteration of insulin binding, or stimulation of a phosphatase activity in non-adherent cells. Expression of Src together with focal adhesion kinase (FAK) in suspended cells restores insulin-induced...

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Share to Cell Adhesion
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Focal Adhesion Kinase 1

Share to Focal Adhesion Protein-Tyrosine Kinases

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Source

Identifiers

PMID: 11696350
DOI: 10.1016/s0014-5793(01)02981-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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