Article
Ileal mucosal bile acid absorption is increased in Cftr knockout mice.
BMC gastroenterology - 1 Jan 2001
Stelzner M, Somasundaram S, Lee S P, Kuver R
Abstract excerpt
BACKGROUND: Excessive loss of bile acids in stool has been reported in patients with cystic fibrosis. Some data suggest that a defect in mucosal bile acid transport may be the mechanism of bile acid malabsorption in these individuals. However, the molecular basis of this defect is unknown. This study examines the expression of the ileal bile acid transporter protein (IBAT) and rates of diffusional (sodium...
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