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Article

Impaired mucosal barrier function in the small intestine of the cystic fibrosis mouse.

Journal of pediatric gastroenterology and nutrition - 1 Oct 2011

De Lisle Robert C, Mueller Racquel, Boyd Megan

Abstract excerpt

OBJECTIVES: The intestinal mucosal barrier protects the body from the large numbers of microbes that inhabit the intestines and the molecules they release. Intestinal barrier function is impaired in humans with cystic fibrosis (CF), including reduced activity of the lipopolysaccharide-detoxifying enzyme intestinal alkaline phosphatase (IAP) and increased permeability. The objective of this study was to determine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21970994
DOI: 10.1097/MPG.0b013e318219c397
PMCID: PMC3188387

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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