Article
Effects of ethnicity on the distribution of clinically relevant endothelial nitric oxide variants.
Pharmacogenetics - 1 Nov 2001
Tanus-Santos J E, Desai M, Flockhart D A
Abstract excerpt
Polymorphisms in the endothelial nitric oxide synthase (eNOS) gene have been associated inconsistently with cardiovascular diseases. A maldistribution of eNOS variants among ethnic groups may explain interethnic differences in nitric oxide (NO)-mediated vasodilation and response to drugs. To test this possibility, we examined the distribution of genetic variants of three clinically relevant eNOS polymorphisms...
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