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Article

Endothelial nitric oxide synthase genotype and ischemic heart disease: meta-analysis of 26 studies involving 23028 subjects.

Circulation - 23 Mar 2004

Casas Juan P, Bautista Leonelo E, Humphries Steve E, Hingorani Aroon D

Abstract excerpt

BACKGROUND: Polymorphisms in the endothelial nitric oxide synthase (eNOS) gene may influence the risk of ischemic heart disease (IHD), but data from published studies with individually low statistical power are conflicting. To evaluate the role of polymorphisms in the eNOS gene in IHD, we considered all available studies in a meta-analysis. METHODS AND RESULTS: Case-control studies evaluating the association...

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PMID: 15007011
DOI: 10.1161/01.CIR.0000121357.76910.A3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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