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Article

Distribution of endothelial nitric oxide synthase gene polymorphisms in Turkish population.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Oct 2009

Sinici Incilay, Karahan Sevilay, Atalar Enver

Abstract excerpt

Nitric oxide (NO) is the major mediator in the regulation of vascular homeostasis. It is synthesized by endothelium from arginine with the catalytic help of endothelial NO synthase (eNOS). Polymorphisms in the eNOS gene have been associated inconsistently with many vascular diseases. Conflicting results may arise from ethnic variations, notably in control-case studies. Therefore, to obtain reliable information...

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PMID: 19730129
DOI: 10.2310/JIM.0b013e3181b91bbd

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