Zebrafish Meis functions to stabilize Pbx proteins and regulate hindbrain patterning.

doi:10.1242/dev.128.21.4139

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Article

Zebrafish Meis functions to stabilize Pbx proteins and regulate hindbrain patterning.

Development (Cambridge, England) - 1 Nov 2001

Waskiewicz A J, Rikhof H A, Hernandez R E, Moens C B

Abstract excerpt

Homeodomain-containing Hox proteins regulate segmental identity in Drosophila in concert with two partners known as Extradenticle (Exd) and Homothorax (Hth). These partners are themselves DNA-binding, homeodomain proteins, and probably function by revealing the intrinsic specificity of Hox proteins. Vertebrate orthologs of Exd and Hth, known as Pbx and Meis (named for a myeloid ecotropic leukemia virus...

Topics

Animals
Body Patterning
DNA-Binding Proteins
Embryo, Nonmammalian
Gene Expression Regulation, Developmental
Genes, Dominant
Homeodomain Proteins
Molecular Sequence Data
Mutation
Myeloid Ecotropic Viral Integration Site 1 Protein
Neoplasm Proteins
Rhombencephalon
Transcription Factors
Zebrafish
Zebrafish Proteins

Source

Open in PubMed

Identifiers

PMID: 11684652
DOI: 10.1242/dev.128.21.4139

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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