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Article

Zebrafish Meis functions to stabilize Pbx proteins and regulate hindbrain patterning.

Development (Cambridge, England) - 1 Nov 2001

Waskiewicz A J, Rikhof H A, Hernandez R E, Moens C B

Abstract excerpt

Homeodomain-containing Hox proteins regulate segmental identity in Drosophila in concert with two partners known as Extradenticle (Exd) and Homothorax (Hth). These partners are themselves DNA-binding, homeodomain proteins, and probably function by revealing the intrinsic specificity of Hox proteins. Vertebrate orthologs of Exd and Hth, known as Pbx and Meis (named for a myeloid ecotropic leukemia virus...

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Identifiers

PMID: 11684652
DOI: 10.1242/dev.128.21.4139

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Zebrafish Meis functions to stabilize Pbx proteins and regulate hindbrain patterning.PMID 11684652Read ↗

Pbx proteins cooperate with Engrailed to pattern the midbrain-hindbrain and diencephalic-mesencephalic boundaries.Semantic proximity Read ↗

Distinct functions of homeodomain-containing and homeodomain-less isoforms encoded by homothorax.Semantic proximity Read ↗

The Homothorax homeoprotein activates the nuclear localization of another homeoprotein, extradenticle, and suppresses eye development in Drosophila.Semantic proximity Read ↗

The role of meis1 in primitive and definitive hematopoiesis during zebrafish developmentSemantic proximity Read ↗

Xenopus Meis3 protein lies at a nexus downstream to Zic1 and Pax3 proteins, regulating multiple cell-fates during early nervous system development.Semantic proximity Read ↗

Engrailed cooperates with extradenticle and homothorax to repress target genes in Drosophila.Semantic proximity Read ↗

spiel ohne grenzen/pou2 is required during establishment of the zebrafish midbrain-hindbrain boundary organizer.Semantic proximity Read ↗

Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype.Semantic proximity Read ↗

The bHLH class protein pMesogenin1 can specify paraxial mesoderm phenotypes.Semantic proximity Read ↗

The homeodomain protein Meis1 is essential for definitive hematopoiesis and vascular patterning in the mouse embryo.Semantic proximity Read ↗

Context-specific function of the LIM homeobox 1 transcription factor in head formation of the mouse embryo.Semantic proximity Read ↗

Altered Hox expression and segmental identity in Mll-mutant mice.Semantic proximity Read ↗

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