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Article

Impaired water maze learning performance without altered dopaminergic function in mice heterozygous for the GDNF mutation.

The European journal of neuroscience - 1 Oct 2001

Gerlai R, McNamara A, Choi-Lundberg D L, Armanini M, Ross J, Powell-Braxton L, Phillips H S

Abstract excerpt

Exogenous glial cell line-derived neurotrophic factor (GDNF) exhibits potent survival-promoting effects on dopaminergic neurons of the nigrostriatal pathway that is implicated in Parkinson's disease and also protects neurons in forebrain ischemia of animal models. However, a role for endogenous GDNF in brain function has not been established. Although mice homozygous for a targeted deletion of the GDNF gene have...

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Source

Identifiers

PMID: 11683907
DOI: 10.1046/j.0953-816x.2001.01724.x

Genes

GDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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