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Article

Striatal hypodopamine phenotypes found in transgenic mice that overexpress glial cell line-derived neurotrophic factor.

Neuroscience letters - 27 Jul 2017

Sotoyama Hidekazu, Iwakura Yuriko, Oda Kanako, Sasaoka Toshikuni, Takei Nobuyuki, Kakita Akiyoshi, Enomoto Hideki, Nawa Hiroyuki

Abstract excerpt

Glial cell line-derived neurotrophic factor (GDNF) positively regulates the development and maintenance of in vitro dopaminergic neurons. However, the in vivo influences of GDNF signals on the brain dopamine system are controversial and not fully defined. To address this question, we analyzed dopaminergic phenotypes of the transgenic mice that overexpress GDNF under the control of the glial Gfap promoter....

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Source

Identifiers

PMID: 28645787
DOI: 10.1016/j.neulet.2017.06.005

Genes

GDNF
RET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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