Article
Glial cell line-derived neurotrophic factor receptor alpha1 availability regulates glial cell line-derived neurotrophic factor signaling: evidence from mice carrying one or two mutated alleles.
Neuroscience - 1 Jan 2000
Tomac A C, Grinberg A, Huang S P, Nosrat C, Wang Y, Borlongan C, Lin S Z, Chiang Y H, Olson L, Westphal H, Hoffer B J
Abstract excerpt
Glial cell line-derived neurotrophic factor receptor alpha1 (GFRalpha1, also known as GDNFR-alpha) is a glycolipid-anchored membrane protein of the GFRalpha family, which binds glial cell line-derived neurotrophic factor [Jing S. et al. (1996) Cell 85, 1113-1124; Treanor J. J. et al. (1996) Nature 382, 80-83], a survival factor for several populations of central and peripheral neurons, including midbrain dopamine...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.