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Animal models of Parkinson’s disease

17 Jan 2012

Abstract excerpt

Animal models of Parkinson's disease (PD) have been widely used in the past four decades to investigate the pathogenesis and pathophysiology of this neurodegenerative disorder. These models have been classically based on the systemic or local (intracerebral) administration of neutoxins that are able to replicate most of the pathological and phenotypic features of PD in mammals (i.e. rodents or primates). In the...

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PMID: 22251459
DOI: 10.1111/j.1742-4658.2012.08491.x

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