Article
Glutathione-S-Transferase M1 null genotype in autoimmune hepatitis.
Digestive diseases and sciences - 1 Oct 2001
Fukagawa N K, Liang P, Li M, Ashikaga T, Reddy K R, Krawitt E L
Abstract excerpt
Autoimmune hepatitis is associated with genes located in the major histocompatibility complex. The search for genes at other loci that may play a role in disease susceptibility and/or severity is an area of active investigation in autoimmune liver diseases. Genes for glutathione-S-transferases, enzymes that are widely distributed and collectively metabolize carcinogens, pollutants, drugs, and a broad spectrum of...
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