Article
A polymorphism in the coding region of interleukin-13 gene is associated with atopy but not asthma in Chinese children.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Oct 2001
Leung T F, Tang N L, Chan I H, Li A M, Ha G, Lam C W
Abstract excerpt
BACKGROUND: Interleukin (IL)-13 is an important cytokine secreted from type 2 helper T lymphocytes. It is essential for modulating IgE synthesis by human B cells. Previous studies showed that polymorphisms in the IL-13 gene were associated with serum total IgE or allergic asthma. The relationship of this marker with sensitization to individual aeroallergens has not been evaluated. OBJECTIVE: We tested whether a...
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