Article
Interleukin-13 receptor A1 gene polymorphism and IL-13 serum level in atopic and non-atopic Egyptian children.
Immunological investigations - 1 Jan 2011
Hussein Yousri M, El-Tarhouny Shereen A, Shalaby Sally M, Mohamed Randa H, Hassan Tamer H, El-Sherbeny Hend M, Mohamed Noha A
Abstract excerpt
OBJECTIVES: To assess serum interleukin (IL) 13 levels in atopic diseases and to determine the role of IL-13R A(1) gene polymorphism (+1398 A/G) in pathogenesis of these diseases. METHODS: Serum total immunoglobulin (Ig) E and IL-13 levels were measured by ELISA and the IL-13R A(1) gene (+1398 A/G) was screened by PCR-restriction fragment length polymorphism (RFLP) in 240 asthmatic children (120 atopic and 120...
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