Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

mei-41 and bub1 block mitosis at two distinct steps in response to incomplete DNA replication in Drosophila embryos.

Current biology : CB - 16 Oct 2001

Garner M, van Kreeveld S, Su T T

Abstract excerpt

Drosophila double park encodes a homolog of Cdt1 that functions in initiation of DNA replication in fission yeast and Xenopus. dup mutants complete the first 15 embryonic cell cycles, presumably via maternal dup products, and show defects in the 16(th) S phase (S16). Cells carrying dup(a1) allele forgo S16 altogether but enter mitosis 16 (M16). We find that the timing of entry into M16 is similar in dup(a1) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anaphase
Share to Chromosomes
Share to Cyclins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Insect Proteins

Share to Metaphase

Share to Mitosis

Share to Protein Kinases

Share to Spindle Apparatus

Source

Identifiers

PMID: 11676920
DOI: 10.1016/s0960-9822(01)00483-3

Genes

ATR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

mei-41 and bub1 block mitosis at two distinct steps in response to incomplete DNA replication in Drosophila embryos.PMID 11676920Read ↗

The Cyclin-dependent kinase inhibitor Dacapo promotes genomic stability during premeiotic S phase.Semantic proximity Read ↗

Levels of the origin-binding protein Double parked and its inhibitor Geminin increase in response to replication stress.Semantic proximity Read ↗

Onset of the DNA replication checkpoint in the early Drosophila embryo.Semantic proximity Read ↗

Drosophila double-parked is sufficient to induce re-replication during development and is regulated by cyclin E/CDK2.Semantic proximity Read ↗

The cyclin-dependent kinase inhibitor Dacapo promotes replication licensing during Drosophila endocycles.Semantic proximity Read ↗

Drosophila double parked: a conserved, essential replication protein that colocalizes with the origin recognition complex and links DNA replication with mitosis and the down-regulation of S phase transcripts.Semantic proximity Read ↗

Saccharomyces cerevisiae BUB2 prevents mitotic exit in response to both spindle and kinetochore damage.Semantic proximity Read ↗

Direct and indirect control of the initiation of meiotic recombination by DNA damage checkpoint mechanisms in budding yeast.Semantic proximity Read ↗

TDM1 Regulation Determines the Number of Meiotic Divisions.Semantic proximity Read ↗

The C-terminus of Bfa1p in budding yeast is essential to induce mitotic arrest in response to diverse checkpoint-activating signals.Semantic proximity Read ↗

The yeast CDC16 and CDC27 genes restrict DNA replication to once per cell cycle.Semantic proximity Read ↗

Spindle assembly checkpoint-related failure perturbs early embryonic divisions and reduces reproductive performance of LT/Sv mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.