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Article

Microphthalmia transcription factor

15 Oct 2001

Abstract excerpt

BACKGROUND: The diagnosis of melanoma can be difficult because of shared cytomorphology with other malignant neoplasms. The most commonly used melanocytic markers, anti-S-100 protein and HMB-45 antigen, have limited specificity and sensitivity, respectively. Microphthalmia transcription factor (Mitf) is a nuclear transcription factor critical for the development and survival of melanocytes and has been shown as a...

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Share to Cutaneous Melanoma Detection and Management
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PMID: 11668469
DOI: 10.1002/cncr.9049

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Microphthalmia-Associated Transcription Factor: A Differentiation Marker in Uveal MelanomaSemantic proximity Read ↗

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Biology and Clinical Relevance of the Micropthalmia Family of Transcription Factors in Human CancerSemantic proximity Read ↗

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Melanocytes and the microphthalmia transcription factor network.Semantic proximity Read ↗

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