Article
Molecular perspectives on cancer, the cell cycle and the inherited disorder ataxia-telangiectasia.
Progress in clinical and biological research - 1 Jan 1997
Brown K D, Tagle D A
Abstract excerpt
Ataxia-Telangiectasia (A-T) is an autosomal recessive disorder which presents a wide array of clinical symptoms including enhanced cancer predisposition and progressive cerebellar degeneration leading to general neuromotor dysfunction. The A-T cellular phenotype consists of higher levels of chrom...
Topics
- Ataxia Telangiectasia
- Cell Cycle
- Genes, Recessive
- Genetic Predisposition to Disease
- Humans
- Multigene Family
- Neoplasms
- Phosphatidylinositol 3-Kinases
- Phosphotransferases (Alcohol Group Acceptor)