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Article

Correlation of pncA sequence with pyrazinamide resistance level in BACTEC for 21 mycobacterium tuberculosis clinical isolates.

Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 2000

Mestdagh M, Realini L, Fonteyne P A, Rossau R, Jannes G, Mijs W, DE Smet K A, Portaels F, Van den Eeckhout E

Abstract excerpt

Mutations in the pncA gene, encoding pyrazinamidase, are considered the major mechanism of pyrazinamide (PZA) resistance in Mycobacterium tuberculosis, but resistant strains containing the wild-type gene have been described. The correlation of pncA sequence with PZA resistance level was examined...

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Identifiers

PMID: 11272256
DOI: 10.1089/mdr.2000.6.283

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11272256-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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