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Article

Characterization of the DNA polymerase gene of varicella-zoster viruses resistant to acyclovir.

The Journal of general virology - 1 Nov 2001

Kamiyama Tomoko, Kurokawa Masahiko, Shiraki Kimiyasu

Abstract excerpt

The nucleotide changes of the DNA polymerase gene and the susceptibility of acyclovir (ACV)-resistant varicella-zoster virus (VZV) mutants to anti-herpetic drugs were determined and compared to those of herpes simplex virus type 1 (HSV-1) mutants. The seven ACV-resistant VZV mutants were classified into three groups, N(779)S, G(805)C and V(855)M, according to the sequences of their DNA polymerase genes. The amino...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11602787
DOI: 10.1099/0022-1317-82-11-2761

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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