Article
Tli1, a resistance locus for carcinogen-induced T-lymphoma.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jun 1999
Wielowieyski A, Brennan L A, Jongstra J
Abstract excerpt
Within 180 days after injection with N-methyl-N-nitrosourea (MNU), 83.5% of AKR/J mice and 37.5% of BALB/cJ mice developed T-lymphoma. The high tumor incidence was a dominant trait, as 93% of MNU-injected F1 mice developed T-lymphoma. A genome screen of 285 MNU-injected F2 mice identified a locus, designated T-lymphoma Induced 1 or Tli1, in a approximately 10-cM interval on central Chr 1 between D1Mit87 and...
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