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Article

The anxiolytic effect of acute ethanol or diazepam exposure is unaltered in mu-opioid receptor knockout mice.

Brain research bulletin - 1 Aug 2001

LaBuda C J, Fuchs P N

Abstract excerpt

Previous researchers demonstrate an opioidergic involvement in the anxiolytic and rewarding actions of ethanol and diazepam. Therefore, to further characterize the role of the opioid system in the anxiolytic action of ethanol and diazepam, normal (C57BL/6J), hybrid (B6129F1) and mu-opioid receptor knockout mice were given i.p. ethanol (0, 1.0 or 1.6 g/kg) or diazepam (1.5 mg/kg). The anxiolytic properties of...

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PMID: 11595359
DOI: 10.1016/s0361-9230(01)00569-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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