Article
Ethanol oral self-administration is increased in mutant mice with decreased beta-endorphin expression.
Brain research - 17 Jul 1999
Grisel J E, Mogil J S, Grahame N J, Rubinstein M, Belknap J K, Crabbe J C, Low M J
Abstract excerpt
The relationship between ethanol (EtOH) administration and the endogenous opioid system has been studied for many years and a considerable body of evidence supports the contention that EtOH modulates the production and/or release of endogenous opioid peptides. However, substantially less is known about the converse influence: the effect that opioids have on EtOH sensitivity. In this study, we used the...
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