Article
Genetic and pharmacological manipulations of the CB(1) receptor alter ethanol preference and dependence in ethanol preferring and nonpreferring mice.
Synapse (New York, N.Y.) - 1 Aug 2008
Vinod K Yaragudri, Yalamanchili Ratnakumar, Thanos Panayotis K, Vadasz Csaba, Cooper Thomas B, Volkow Nora D, Hungund Basalingappa L
Abstract excerpt
Recent studies have indicated a role for the endocannabinoid system in ethanol-related behaviors. This study examined the effect of pharmacological activation, blockade, and genetic deletion of the CB(1) receptors on ethanol-drinking behavior in ethanol preferring C57BL/6J (B6) and ethanol nonpre...
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